What is the route for medications administered underneath the tongue that need to dissolve?

The sublingual route is the method of administration for medications placed under the tongue that are designed to dissolve and be absorbed directly into the bloodstream through the mucous membranes. This route allows for rapid absorption because it bypasses the digestive system and the first-pass metabolism in the liver, which is especially important for certain medications that may be ineffective if processed through the gastrointestinal tract.

In contrast, the buccal route involves placing the medication between the gums and cheek, which is different in its absorption mechanics and does not specifically involve the area under the tongue. The parenteral route relates to medications administered via injections (intravenous, intramuscular, subcutaneous, etc.), which is another distinct delivery method. The oral route refers to swallowing medications, which requires them to pass through the digestive system, leading to a slower onset of action compared to sublingual administration.