When applying a transdermal patch, which area should be avoided?

When applying a transdermal patch, it is crucial to avoid placing it on scars and callouses. This is because scars and callouses can alter the absorption of the medication contained in the patch. These areas may have a different thickness or texture compared to normal skin, which can hinder the patch's ability to adhere properly and can lead to inconsistent or reduced medication delivery. Ensuring optimal skin condition allows for reliable absorption, making it essential to select intact, healthy skin when administering transdermal medication. Other options, such as applying on dry skin or on arms or legs, are typically acceptable provided the skin is intact and healthy.